Clinical Trials

• CHANCE-3

  Official TitleColchicine in High-risk Patients With Acute Minor-to-moderate Ischemic Stroke or Transient Ischemic Attack (CHANCE-3)Brief SummaryThis study is a multicentre, randomized, double-blind, placebo-controlled, investigator-sponsored study that aims to investigate the efficacy of colchicine …more>>

• PUMICE

  Official TitleRecombinant Human Prourokinase（rhPro-UK）for Injection Versus Standard Medical Treatment for Acute Mild Ischemic Stroke (NIHSS≤5) Within 4.5 Hours After Symptom OnsetBrief SummaryThe purpose of this study is to investigate the safety and efficacy of rhPro-UK (35mg) versus standard med…more>>

• TRACE-3

  Official TitleA Phase 3, Multicenter, Prospective, Randomized, Open Label, Blinded-endpoint (PROBE) Controlled Trial of Recombinant Human TNK Tissue-type Plasminogen Activator (rhTNK-tPA) for Injection Versus Standard Medical Treatment for Acute Ischemic Stroke Due to Large Vessel Occlusion With Per…more>>

• DAISY

  Official TitleA Phase II, Randomized, Double-blind, Placebo-controlled, Dose-Finding, Multi-center Study to Assess the Efficacy and Safety of Dengzhanxixin Injection in Patients With Acute Ischemic Stroke Receiving Reperfusion TherapyBrief SummaryTo assess the Efficacy and Safety of Dengzhanxixin In…more>>

• TASTE-2

  Official TitleTreatment of Acute Ischemic STroke With Edaravone Dexborneol Ⅱ (TASTE-2)Brief SummaryThis study is a multicentre, randomized, double-blind, placebo parallel controlled, investigator-sponsored study that aims to investigate the efficacy and safety of Edaravone Dexborneol treatment in pa…more>>

• INSURE

  Official TitleINdobufen Versus aSpirin in acUte Ischemic stRokE（INSURE）Brief SummaryChina has the largest burden of cerebrovascular disease in the world. About 60% to 80% of which are ischemic stroke. In recent years, stroke has replaced heart disease and tumor diseases as the first cause of death…more>>

• CHANCE-2

  Official TitleClopidogrel With Aspirin in High-risk Patients With Acute Non-disabling Cerebrovascular Events II (CHANCE-II)Brief SummaryThe primary objective of this trial is to assess the effects of ticagrelor plus aspirin versus clopidogrel plus aspirin on reducing the 3-month risk of any stroke (…more>>

• FAVORITE

  Official TitleEfficacy and safety of Ferrous iron on the prevention of Vascular cOgnitive impaiRment among patients with cerebral Infarction/TIA（FAVORITE)Brief SummaryThe prevalence of Vascular Cognitive Impairment(VCI) is high in patients after ischemic stroke or transient ischemic attack(TIA) . E…more>>

• ANGEL-REBOOT

  Official TitleRandomized Study of Bailout Intracranial Angioplasty Following Thrombectomy for Acute Large Vessel Occlusion: A Multi-centered, Prospective, Open-label, Blind Endpoint, Randomized Controlled Trial (ANGEL-REBOOT)Brief SummaryUnfavorable outcomes were associated with failed thrombectomy …more>>

• BASIS

  Official TitleA Multicenter, Prospective, Randomized, Open-label, Blinded End-point Clinical Study to Evaluate the Safety and Efficacy of Intracranial Balloon Angioplasty Plus Aggressive Medical Management for Symptomatic Intracranial Artery Stenosis (BASIS)Brief SummaryIntracranial atherosclerotic …more>>

• CANDOR

  Official TitleChina National Clinical Research Center Alzheimer's Disease and Neurodegenerative Disorder Research (CANDOR)Brief SummaryThis is a multi-center study that has three cohorts: 1) cognitive normal cohort (CN), 2) Alzheimer's disease cohort (AD) and 3) vascular cognitive impairment…more>>

• FAITH

  Official TitleFolic Acid and Intensive Antihypertensive Therapy for Cerebrovascular and Cardiovascular Events Prevention Among Patients With Hypertension and Cerebral Small Vascular Diseases (FAITH)----A Multicenter, Randomized, Controlled, Open-label, 2x2 Factorial, Blinded End-point TrialBrief Sum…more>>

• GOLDEN BRIDGE II

  Official TitleA Multi-centre, Cluster Randomized Controlled Trial of an Artificial Intelligence-Based Clinical Decision Support System for Integrated Management of Patients With Acute Ischemic Stroke: The GOLDEN BRIDGE II Trial（GOLDEN BRIDGE II ）Brief SummaryThis study will conduct a cluster rando…more>>

• MERCURY

  Official TitleCorrelation Patterns of Brain Temperature-Pressure in Acute Brain Injury：a Multicenter Prospective Cohort Study（MERCURY）Brief SummaryThe goal of this prospective, multicenter, observational, cohort trail is to explore the pattern of brain temperature-brain pressure association in ac…more>>

• CATIS-2

  Official TitleChina Antihypertensive Trial in Acute Ischemic Stroke II(CATIS-2)Brief SummaryThe investigators propose to conduct a multicenter randomized trial to test the primary hypothesis of whether early antihypertensive treatment starting between the first 24-48 hours after the onset of an acut…more>>

• INSPIRES

  Official TitleIntensive Statin and Antiplatelet Therapy for High-risk Intracranial or Extracranial Atherosclerosis (INSPIRES)Brief SummaryLarge-artery stenosis plays an important role in the occurrence of ischemic stroke. The primary purpose of this study is to evaluate the efficacy and safety of in…more>>

• CHANCE

  Official TitleRandomized,Double-blind Trial Comparing the Effects of a 3-month Clopidogrel Regimen,Combined With ASA During the First 21days,Versus ASA Alone for the Acute Treatment of TIA or Minor Stroke(CHANCE)Brief SummaryThe purpose of this study is to assess the effects of a 3-month regimen of …more>>

• SICH

  Official TitleSafety of Stromal Vascular Fraction (SVF) Therapy in Patients With Acute Spontaneous Intracerebral Hemorrhage (SICH): a Phase I Clinical StudyBrief SummaryThe purpose of this pilot study is to evaluate the safety of stromal vascular fraction (SVF) therapy in patients with spontaneous i…more>>

• CBS-ICH

  Official TitleDeproteinised Calf Blood Serum Injection for the Treatment of Acute Intracerebral Hemorrhage(CBS-ICH)Brief SummaryThe purpose of this study is to investigate the efficacy and safety of Deproteinised Calf Blood Serum Injection in alleviating perihematomal edema (PHE) and secondary brain…more>>